Information for physicians and pharmacists about drugs that might cause dry mouth: a study of monographs and published literature.
Identifieur interne : 000216 ( Main/Exploration ); précédent : 000215; suivant : 000217Information for physicians and pharmacists about drugs that might cause dry mouth: a study of monographs and published literature.
Auteurs : Caroline T. Nguyen [Canada] ; Michael I. Macentee ; Barbara Mintzes ; Thomas L. PerrySource :
- Drugs & aging [ 1179-1969 ] ; 2014.
Descripteurs français
- KwdFr :
- MESH :
- métabolisme : Salive.
- statistiques et données numériques : Services d'information sur les médicaments.
- Effets secondaires indésirables des médicaments, Humains, Médecins, Ordonnances médicamenteuses, Pharmaciens.
English descriptors
- KwdEn :
- MESH :
- metabolism : Saliva.
- statistics & numerical data : Drug Information Services.
- Drug Prescriptions, Drug-Related Side Effects and Adverse Reactions, Humans, Pharmacists, Physicians.
Abstract
BACKGROUND
Over three-quarters of the older population take medications that can potentially cause dry mouth. Physicians or pharmacists rarely inform patients about this adverse effect and its potentially severe damage to the teeth, mouth and general health.
OBJECTIVES
The objectives of this study were to (1) identify warnings in the literature about dry mouth associated with the most frequently prescribed pharmaceutical products in Canada; and (2) consider how this information might be obtained by physicians, pharmacists and patients.
METHODS
Monographs on the 72 most frequently prescribed medications during 2010 were retrieved from the Compendium of Pharmaceuticals and Specialties (CPS, a standard drug information reference for physicians and pharmacists), the National Library of Medicine's 'DailyMed' database, directly from the manufacturers, and from a systematic search of biomedical journals.
RESULTS
The CPS provided monographs for 43% of the medications, and requests to manufacturers produced the remaining monographs. Mentions of dry mouth were identified in 61% of the products (43% amongst CPS monographs; an additional 43% amongst manufacturers' monographs; 7% in the DailyMed database and 7% from biomedical journals); five medications had contradictory reports in different monographs.
CONCLUSION
Nearly two-thirds (61%) of the most commonly prescribed medications can cause dry mouth, yet warnings about this adverse effect and its potentially serious consequences are not readily available to physicians, pharmacists, dentists or patients.
DOI: 10.1007/s40266-013-0141-5
PubMed: 24293180
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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Nguyen</name><affiliation wicri:level="4"><nlm:affiliation>Department of Oral Health Sciences, Faculty of Dentistry, The University of British Columbia, RM 374, 2199 Wesbrook Mall, Vancouver, BC, V6T1Z3, Canada, caroline.nguyen@ubc.ca.</nlm:affiliation><country wicri:rule="url">Canada</country><wicri:regionArea>Department of Oral Health Sciences, Faculty of Dentistry, The University of British Columbia, RM 374, 2199 Wesbrook Mall, Vancouver, BC, V6T1Z3, Canada</wicri:regionArea><orgName type="university">Université de la Colombie-Britannique</orgName><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique </region></placeName></affiliation></author><author><name sortKey="Macentee, Michael I" sort="Macentee, Michael I" uniqKey="Macentee M" first="Michael I" last="Macentee">Michael I. Macentee</name></author><author><name sortKey="Mintzes, Barbara" sort="Mintzes, Barbara" uniqKey="Mintzes B" first="Barbara" last="Mintzes">Barbara Mintzes</name></author><author><name sortKey="Perry, Thomas L" sort="Perry, Thomas L" uniqKey="Perry T" first="Thomas L" last="Perry">Thomas L. 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Nguyen</name><affiliation wicri:level="4"><nlm:affiliation>Department of Oral Health Sciences, Faculty of Dentistry, The University of British Columbia, RM 374, 2199 Wesbrook Mall, Vancouver, BC, V6T1Z3, Canada, caroline.nguyen@ubc.ca.</nlm:affiliation><country wicri:rule="url">Canada</country><wicri:regionArea>Department of Oral Health Sciences, Faculty of Dentistry, The University of British Columbia, RM 374, 2199 Wesbrook Mall, Vancouver, BC, V6T1Z3, Canada</wicri:regionArea><orgName type="university">Université de la Colombie-Britannique</orgName><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique </region></placeName></affiliation></author><author><name sortKey="Macentee, Michael I" sort="Macentee, Michael I" uniqKey="Macentee M" first="Michael I" last="Macentee">Michael I. 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Perry</name></author></analytic><series><title level="j">Drugs & aging</title><idno type="eISSN">1179-1969</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Drug Information Services (statistics & numerical data)</term><term>Drug Prescriptions (MeSH)</term><term>Drug-Related Side Effects and Adverse Reactions (MeSH)</term><term>Humans (MeSH)</term><term>Pharmacists (MeSH)</term><term>Physicians (MeSH)</term><term>Saliva (metabolism)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Effets secondaires indésirables des médicaments (MeSH)</term><term>Humains (MeSH)</term><term>Médecins (MeSH)</term><term>Ordonnances médicamenteuses (MeSH)</term><term>Pharmaciens (MeSH)</term><term>Salive (métabolisme)</term><term>Services d'information sur les médicaments (statistiques et données numériques)</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Saliva</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Salive</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Drug Information Services</term></keywords><keywords scheme="MESH" qualifier="statistiques et données numériques" xml:lang="fr"><term>Services d'information sur les médicaments</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Drug Prescriptions</term><term>Drug-Related Side Effects and Adverse Reactions</term><term>Humans</term><term>Pharmacists</term><term>Physicians</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Effets secondaires indésirables des médicaments</term><term>Humains</term><term>Médecins</term><term>Ordonnances médicamenteuses</term><term>Pharmaciens</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b></p><p>Over three-quarters of the older population take medications that can potentially cause dry mouth. Physicians or pharmacists rarely inform patients about this adverse effect and its potentially severe damage to the teeth, mouth and general health.</p></div><div type="abstract" xml:lang="en"><p><b>OBJECTIVES</b></p><p>The objectives of this study were to (1) identify warnings in the literature about dry mouth associated with the most frequently prescribed pharmaceutical products in Canada; and (2) consider how this information might be obtained by physicians, pharmacists and patients.</p></div><div type="abstract" xml:lang="en"><p><b>METHODS</b></p><p>Monographs on the 72 most frequently prescribed medications during 2010 were retrieved from the Compendium of Pharmaceuticals and Specialties (CPS, a standard drug information reference for physicians and pharmacists), the National Library of Medicine's 'DailyMed' database, directly from the manufacturers, and from a systematic search of biomedical journals.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>The CPS provided monographs for 43% of the medications, and requests to manufacturers produced the remaining monographs. Mentions of dry mouth were identified in 61% of the products (43% amongst CPS monographs; an additional 43% amongst manufacturers' monographs; 7% in the DailyMed database and 7% from biomedical journals); five medications had contradictory reports in different monographs.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSION</b></p><p>Nearly two-thirds (61%) of the most commonly prescribed medications can cause dry mouth, yet warnings about this adverse effect and its potentially serious consequences are not readily available to physicians, pharmacists, dentists or patients.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">24293180</PMID><DateCompleted><Year>2014</Year><Month>09</Month><Day>30</Day></DateCompleted><DateRevised><Year>2018</Year><Month>12</Month><Day>02</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1179-1969</ISSN><JournalIssue CitedMedium="Internet"><Volume>31</Volume><Issue>1</Issue><PubDate><Year>2014</Year><Month>Jan</Month></PubDate></JournalIssue><Title>Drugs & aging</Title><ISOAbbreviation>Drugs Aging</ISOAbbreviation></Journal><ArticleTitle>Information for physicians and pharmacists about drugs that might cause dry mouth: a study of monographs and published literature.</ArticleTitle><Pagination><MedlinePgn>55-65</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1007/s40266-013-0141-5</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Over three-quarters of the older population take medications that can potentially cause dry mouth. Physicians or pharmacists rarely inform patients about this adverse effect and its potentially severe damage to the teeth, mouth and general health.</AbstractText><AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">The objectives of this study were to (1) identify warnings in the literature about dry mouth associated with the most frequently prescribed pharmaceutical products in Canada; and (2) consider how this information might be obtained by physicians, pharmacists and patients.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Monographs on the 72 most frequently prescribed medications during 2010 were retrieved from the Compendium of Pharmaceuticals and Specialties (CPS, a standard drug information reference for physicians and pharmacists), the National Library of Medicine's 'DailyMed' database, directly from the manufacturers, and from a systematic search of biomedical journals.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">The CPS provided monographs for 43% of the medications, and requests to manufacturers produced the remaining monographs. Mentions of dry mouth were identified in 61% of the products (43% amongst CPS monographs; an additional 43% amongst manufacturers' monographs; 7% in the DailyMed database and 7% from biomedical journals); five medications had contradictory reports in different monographs.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Nearly two-thirds (61%) of the most commonly prescribed medications can cause dry mouth, yet warnings about this adverse effect and its potentially serious consequences are not readily available to physicians, pharmacists, dentists or patients.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Nguyen</LastName><ForeName>Caroline T</ForeName><Initials>CT</Initials><AffiliationInfo><Affiliation>Department of Oral Health Sciences, Faculty of Dentistry, The University of British Columbia, RM 374, 2199 Wesbrook Mall, Vancouver, BC, V6T1Z3, Canada, caroline.nguyen@ubc.ca.</Affiliation></AffiliationInfo></Author><Author 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